Lab test, inflammation

Erythrocyte sedimentation rate (ESR)

Related terms: ESR, Sed rate, Sedimentation rate

EstablishedTextbook physiology, or consistent findings reflected in national guidance.
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In brief

Measures how fast red blood cells settle in a tube of blood, a general sign of inflammation.

What it measures

How fast red blood cells settle to the bottom of a tall tube of blood.

Why it is done

To help diagnose conditions linked with inflammation, including infections, cancers and autoimmune diseases. It cannot show the cause or where the inflammation is.

Reading the results

  • A high ESR suggests inflammation somewhere in the body.
  • A normal ESR does not rule out active disease.
  • ESR is not as accurate as CRP in most situations.

Females tend to have a slightly higher ESR.

Before the test

None.

What can affect the result

  • Pregnancy
  • Periods
  • Ageing
  • Alcohol
  • Some medicines and supplements

Related topics

Sources

  1. Erythrocyte sedimentation rate (ESR)Pathology Tests Explained, last reviewed 18 May 2025

Test information summarised from the sources listed on this page, read on 19 October 2026. General education only, not medical advice. Spotted a mistake? Please tell us through the HuBu-Intel contact page.

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