Supplement

Ashwagandha

Related terms: Withania somnifera, Indian ginseng, Winter cherry

EmergingEarly, mixed or mostly laboratory and animal evidence. Not settled.
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In brief

A herb used in Ayurvedic and other traditional medicine, often promoted for stress, anxiety and sleep. The TGA has warned of very rare liver injury.

  • The TGA issued a safety advisory on ashwagandha in 2024.
  • Ashwagandha should be avoided during pregnancy and should not be used while breastfeeding.
  • It may interact with medicines for diabetes, blood pressure, thyroid conditions and seizures, with sedatives, and with medicines that suppress the immune system.

How it works

Some ashwagandha preparations may be effective for insomnia and stress, according to the US National Center for Complementary and Integrative Health, but its effects on anxiety are unclear. It may be safe when taken short term, up to 3 months.

Cases of liver injury linked with ashwagandha continue to be reported to the Therapeutic Goods Administration, though the risk appears to be very rare. If you notice yellow skin or eyes, dark urine or unusual tiredness, stop taking it and seek medical advice, and avoid it if you have or have had liver problems.

Connections

3 connections on the map. Select a topic to read its page.

Ashwagandha affects LiverLiverAshwagandha has been studied for Chronic stress (allostatic load)Chronic stressAshwagandha has been studied for Trouble sleepingTrouble sleepingAshwagandha affects LiverLiverAshwagandha has been studied for Chronic stress (allostatic load)Chronic stressAshwagandha has been studied for Trouble sleepingTrouble sleeping

Ashwagandha has been studied for

Ashwagandha affects

Medicines and supplements

General education only. Never start, stop or change a medicine without your prescriber.

Sources

  1. AshwagandhaNIH NCCIH, last reviewed March 2023
  2. Withania somnifera (ashwagandha) and liver injuryTherapeutic Goods Administration

Each connection above names its own source. See every source AskBioMap uses.

Summarised from the NIH National Center for Complementary and Integrative Health and the Therapeutic Goods Administration. Sources read on 13 October 2026. General education only, not medical advice. Spotted a mistake? Please tell us through the HuBu-Intel contact page.

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