Condition

Fatty liver disease (MAFLD)

Related terms: Fatty liver, MAFLD, MASLD, NAFLD, Metabolic associated fatty liver disease

EstablishedTextbook physiology, or consistent findings reflected in national guidance.
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In brief

Too much fat stored in the liver. It affects about 1 in every 3 Australian adults, and in most people the liver damage can be reversed.

  • There are no medicines to treat fatty liver disease, according to healthdirect.
  • Yellow eyes and skin (jaundice), bruising or vomiting blood can be signs of more serious liver disease.
  • Complications can include heart problems, stroke, kidney disease and liver cancer.

How it works

The main type, metabolic associated fatty liver disease (MAFLD), used to be called non-alcoholic fatty liver disease (NAFLD), and the other main type is alcohol-related. Common causes are being overweight, especially around the abdomen, type 2 diabetes or insulin resistance, high cholesterol or triglycerides, and drinking too much alcohol. Less common causes include an underactive thyroid, some medicines and PCOS.

Fatty liver usually causes no symptoms and is often found with blood tests, including liver function tests, or an ultrasound. The extra fat causes liver inflammation, which leads to scarring (fibrosis) and may lead to cirrhosis. Lifestyle changes can improve fatty liver and even reverse it, including losing weight if needed, exercising regularly and drinking little or no alcohol.

Connections

5 connections on the map. Select a topic to read its page.

Fatty liver disease (MAFLD) affects LiverLiverFatty liver disease (MAFLD) can be caused by AlcoholAlcoholFatty liver disease (MAFLD) can result from Insulin resistanceInsulin resistanceFatty liver disease (MAFLD) is linked with Hypothyroidism (underactive thyroid)HypothyroidismFatty liver disease (MAFLD) is measured by Liver function tests (LFTs)Liver function testsFatty liver disease (MAFLD) affects LiverLiverFatty liver disease (MAFLD) can be caused by AlcoholAlcoholFatty liver disease (MAFLD) can result from Insulin resistanceInsulin resistanceFatty liver disease (MAFLD) is linked with Hypothyroidism (underactive thyroid)HypothyroidismFatty liver disease (MAFLD) is measured by Liver function tests (LFTs)Liver function tests

Fatty liver disease (MAFLD) affects

Fatty liver disease (MAFLD) can result from

Fatty liver disease (MAFLD) can be caused by

Fatty liver disease (MAFLD) is linked with

Fatty liver disease (MAFLD) is measured by

Lab tests

Sources

  1. Fatty liver diseasehealthdirect Australia, last reviewed March 2025
  2. Liver function testsPathology Tests Explained, last reviewed 27 July 2025
  3. LiverBetter Health Channel (Victorian Government), last reviewed 29 July 2026

Each connection above names its own source. See every source AskBioMap uses.

Summarised from healthdirect, Pathology Tests Explained and the Better Health Channel. Sources read on 13, 16 and 19 October 2026. General education only, not medical advice. Spotted a mistake? Please tell us through the HuBu-Intel contact page.

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