Body system

Thyroid gland

Related terms: Thyroid, Thyroid hormones, HPT axis

EstablishedTextbook physiology, or consistent findings reflected in national guidance.
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In brief

A gland at the front of the neck that makes thyroid hormones, which regulate metabolism, including growth and how much energy the body uses.

  • An underactive thyroid can cause tiredness, feeling cold, weight gain, constipation, dry skin, hair loss and low mood.
  • An overactive thyroid can cause a rapid pulse, shaking hands, sweating, weight loss and anxiety.
  • Hashimoto's disease is the most common cause of an underactive thyroid in Australia, according to healthdirect. Graves' disease is the most common cause of an overactive thyroid.

How it works

The thyroid uses iodine to make two main hormones, thyroxine (T4) and tri-iodothyronine (T3). T3 is more active but is made in smaller amounts. The more T3 and T4 in the blood, the faster the metabolism. Thyroid hormones also influence energy levels, body temperature and calcium levels.

The pituitary gland controls the thyroid by producing thyroid stimulating hormone (TSH). When thyroid hormone is low, the pituitary makes more TSH, and when it is high, the pituitary makes less, which is why TSH is the first thyroid blood test.

Connections

5 connections on the map. Select a topic to read its page.

Thyroid gland includes Thyroid hormone productionThyroid hormone productionThyroid gland is linked with Heart palpitationsHeart palpitationsThyroid gland is measured by Thyroid function tests (TSH, free T4, free T3)Thyroidfunction testsThyroid gland is part of Hormone (endocrine) systemHormone systemThyroid gland makes Thyroid hormones (T4 and T3)Thyroid hormonesThyroid gland includes Thyroid hormone productionThyroid hormoneproductionThyroid gland is linked with Heart palpitationsHeart palpitationsThyroid gland is measured by Thyroid function tests (TSH, free T4, free T3)Thyroid function testsThyroid gland is part of Hormone (endocrine) systemHormone systemThyroid gland makes Thyroid hormones (T4 and T3)Thyroid hormones

Thyroid gland is part of

Thyroid gland includes

Thyroid gland makes

Thyroid gland is linked with

Thyroid gland is measured by

Lab tests

Medicines and supplements

General education only. Never start, stop or change a medicine without your prescriber.

Sources

  1. Thyroid glandBetter Health Channel (Victorian Government), last reviewed 6 December 2015
  2. Endocrine glands and their hormoneshealthdirect Australia, last reviewed December 2024
  3. Hypothyroidism (underactive thyroid)healthdirect Australia, last reviewed October 2024
  4. Thyroid function testsPathology Tests Explained, last reviewed 9 January 2025
  5. Foods high in iodinehealthdirect Australia, last reviewed April 2025

Each connection above names its own source. See every source AskBioMap uses.

Summarised from the Better Health Channel, healthdirect and Pathology Tests Explained. Sources read on 13, 16 and 19 October 2026. General education only, not medical advice. Spotted a mistake? Please tell us through the HuBu-Intel contact page.

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