Condition

Depression

Related terms: Major depression, Clinical depression, Depressive disorder, MDD

EstablishedTextbook physiology, or consistent findings reflected in national guidance.
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In brief

One of the most common mental health conditions. It affects how you feel, think and behave, with symptoms lasting 2 weeks or more. Help works best when it starts early.

  • Your GP is a good place to start, according to healthdirect.
  • If you or someone you know is in immediate danger, call triple zero (000). To talk to someone now, call Lifeline on 13 11 14.
  • Having a family member with depression does not mean you will develop it yourself.

How it works

Symptoms include feeling sad, teary or overwhelmed most of the time, losing interest in activities you once enjoyed, difficulty sleeping or feeling tired during the day, changes in appetite and weight, feeling run down, and losing interest in sex.

Causes include ongoing stress or life events such as losing a job, family history, medical conditions that affect how the brain regulates mood, and drug and alcohol use. Complex chemical changes occur in the body, particularly in the brain. Treatments include talking therapies such as CBT, medicines, and lifestyle changes such as reducing substance use, improving sleep and exercising.

Looking after it

If you or someone you know is having suicidal thoughts and is in immediate danger, call triple zero (000). To talk to someone now, call Lifeline on 13 11 14 or Beyond Blue on 1300 22 4636.

Connections

11 connections on the map. Select a topic to read its page.

Depression can be raised by Loneliness and isolationLoneliness and isolationDepression can be raised by Overweight and obesityOverweightand obesityDepression can be raised by Sitting timeSitting timeDepression can cause Brain fogBrain fogDepression can cause Tiredness and fatigueTirednessand fatigueDepression can cause Low sex driveLow sex driveDepression can cause Trouble sleepingTrouble sleepingDepression can raise DementiaDementiaDepression is linked with COPD (chronic obstructive pulmonary disease)COPDDepression is linked with Low mood and low motivationLow mood andlow motivationDepression is linked with PsoriasisPsoriasisDepression can be raised by Overweight and obesityOverweight and obesityDepression can be raised by Sitting timeSitting timeDepression can cause Tiredness and fatigueTiredness and fatigueDepression can cause Trouble sleepingTrouble sleepingDepression can raise DementiaDementiaDepression is linked with COPD (chronic obstructive pulmonary disease)COPDDepression is linked with Low mood and low motivationLow mood andlow motivationDepression is linked with PsoriasisPsoriasisand 3 more below

Depression can cause

Depression is linked with

Depression can be raised by

Depression can raise

Medicines and supplements

General education only. Never start, stop or change a medicine without your prescriber.

Sources

  1. Depressionhealthdirect Australia, last reviewed November 2025
  2. Lifeline crisis supportLifeline Australia
  3. Beyond Blue support serviceBeyond Blue

Each connection above names its own source. See every source AskBioMap uses.

Summarised from healthdirect and Lifeline. Sources read on 12 and 16 October 2026. General education only, not medical advice. Spotted a mistake? Please tell us through the HuBu-Intel contact page.

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